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                                (S)-(+)-Ketoprofen

                                右旋酮洛芬;(S)-Ketoprofen;Dexketoprofen

                                收藏商品 产品说明书
                                货号 abs816915
                                规格 价格
                                ¥395
                                库存?#21050;?/span>1-2周
                                ¥578
                                库存?#21050;?/span>1-2周
                                ¥755
                                库存?#21050;?/span>1-2周
                                ¥1055
                                库存?#21050;?/span>1-2周

                                数量:

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                                概述
                                描述

                                Dexketoprofen works by blocking the action of a substance in the body called cyclo-oxygenase. It belongs to a class of medicines called non-steroidal anti-inflammatory drugs (NSAIDs). Cyclo-oxygenase is involved in the production of chemicals in the body called prostaglandins. Prostaglandins are produced in response to injury or certain diseases and would otherwise go on to cause swelling, inflammation and pain. By blocking cyclo-oxygenase, dexketoprofen prevents the production of prostaglandins and therefore reduces inflammation and pain. Along with Peripheral analgesic action it possesses central analgesic action. Dexketoprofen is a non-steroidal anti-inflammatory drug. It is manufactured by Menarini, under the tradename Keral. It is available in the UK, as dexketoprofen trometamol, as a prescription-only drug and in Latin America as Miracox, produced by Stein in Costa Rica. In Italy it is available as an over the counter-drug under the tradename Enantyum. In Lithuania it is available as over the counter-drug uder tradename Dolmen.

                                别名 右旋酮洛芬;(S)-Ketoprofen;Dexketoprofen
                                靶点 COX-1;COX-2
                                性能
                                外观 白色结晶性粉末
                                保存方法 store at -20℃ for one year(Powder);
                                in DMSO or others solvent store at 2-4℃ for two weeks, at -20℃ for six months.
                                纯度 99%
                                分子量 254.3
                                分子结构式
                                化学式 C16H14O3
                                溶解性 Water : 51 mg/L
                                DMSO : ≥ 125 mg/mL (491.58 mM)
                                CAS号 22161-81-5
                                参考文献

                                1. Pelligand L, et al. J Vet Pharmacol Ther. 2014 Aug;37(4):354-66.

                                2. Zhou SF, et al. Curr Med Chem. 2009; 16(27):3480-675.

                                3. Reid G, et al. Proc Natl Acad Sci U S A. 2003 Aug 5;100(16):9244-9.

                                4. Shitara Y, et al. Pharm Res. 2002 Feb; 19(2):147-53.

                                5. Takeda M, et al. J Pharmacol Exp Ther. 2002 Aug; 302(2): 666-71.


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